Annual Review of Pharmacology and Toxicology-Volume 48, 2008

Annual Review of Pharmacology and Toxicology-Volume 48, 2008

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences Jean-Marc Pascussi, Sabine Gerbal-Chaloin, Cdric Duret, Martine Daujat-Chavanieu, Marie-Jos Vilarem, Patrick Maurel Annual Review of Pharmacology and Toxicology, Vol. 48: 1-32 (Volume publication date February 2008)
Abstract | Full Text | PDF (164 KB)
Mechanisms of Placebo and Placebo-Related Effects Across Diseases and Treatments Fabrizio Benedetti Annual Review of Pharmacology and Toxicology, Vol. 48: 33-60 (Volume publication date February 2008)
Abstract | Full Text | PDF (404 KB)
Pharmacotherapy for the Treatment of Choroidal Neovascularization Due to Age-Related Macular Degeneration Gary D. Novack Annual Review of Pharmacology and Toxicology, Vol. 48: 61-78 (Volume publication date February 2008)
Abstract | Full Text | PDF (113 KB)
Nicotinic Acid: Pharmacological Effects and Mechanisms of Action Andreas Gille, Erik T. Bodor, Kashan Ahmed, Stefan Offermanns Annual Review of Pharmacology and Toxicology, Vol. 48: 79-106 (Volume publication date February 2008)
Abstract | Full Text | PDF (833 KB)
Activation of G ProteinCoupled Receptors: Beyond Two-State Models and Tertiary Conformational Changes Paul S.-H. Park, David T. Lodowski, Krzysztof Palczewski Annual Review of Pharmacology and Toxicology, Vol. 48: 107-141 (Volume publication date February 2008)
Abstract | Full Text | PDF (972 KB)
Apoptin: Therapeutic Potential of an Early Sensor of Carcinogenic Transformation Claude Backendorf , Astrid E. Visser , A.G. de Boer , Rhyenne Zimmerman , Mijke Visser , Patrick Voskamp , Ying-Hui Zhang , Mathieu Noteborn Annual Review of Pharmacology and Toxicology, Vol. 48: 143-169 (Volume publication date February 2008)
Abstract | Full Text | PDF (328 KB)
Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation Antonella Viola, Andrew D. Luster Annual Review of Pharmacology and Toxicology, Vol. 48: 171-197 (Volume publication date February 2008)
Abstract | Full Text | PDF (1037 KB)
Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response Kohsuke Takeda, Takuya Noguchi, Isao Naguro, Hidenori Ichijo Annual Review of Pharmacology and Toxicology, Vol. 48: 199-225 (Volume publication date February 2008)
Abstract | Full Text | PDF (333 KB)
Pharmacogenetics of Anti-HIV Drugs A. Telenti, U. M. Zanger Annual Review of Pharmacology and Toxicology, Vol. 48: 227-256 (Volume publication date February 2008)
Abstract | Full Text | PDF (227 KB)
Epigenetics and Complex Disease: From Etiology to New Therapeutics Carolyn Ptak , Arturas Petronis Annual Review of Pharmacology and Toxicology, Vol. 48: 257-276 (Volume publication date February 2008)
Abstract | Full Text | PDF (119 KB)
Vesicular Neurotransmitter Transporters as Targets for Endogenous and Exogenous Toxic Substances Farrukh A. Chaudhry, Robert H. Edwards, Frode Fonnum Annual Review of Pharmacology and Toxicology, Vol. 48: 277-301 (Volume publication date February 2008)
Abstract | Full Text | PDF (258 KB)
Mechanism-Based Concepts of Size and Maturity in Pharmacokinetics B.J. Anderson, N.H.G. Holford Annual Review of Pharmacology and Toxicology, Vol. 48: 303-332 (Volume publication date February 2008)
Abstract | Full Text | PDF (336 KB)
Role of CYP1B1 in Glaucoma Vasilis Vasiliou, Frank J. Gonzalez Annual Review of Pharmacology and Toxicology, Vol. 48: 333-358 (Volume publication date February 2008)
Abstract | Full Text | PDF (208 KB)
Caveolae as Organizers of Pharmacologically Relevant Signal Transduction Molecules Hemal H. Patel, Fiona Murray, Paul A. Insel Annual Review of Pharmacology and Toxicology, Vol. 48: 359-391 (Volume publication date February 2008)
Abstract | Full Text | PDF (289 KB)
Proteases for Processing Proneuropeptides into Peptide Neurotransmitters and Hormones Vivian Hook, Lydiane Funkelstein, Douglas Lu, Steven Bark, Jill Wegrzyn, Shin-Rong Hwang Annual Review of Pharmacology and Toxicology, Vol. 48: 393-423 (Volume publication date February 2008)
Abstract | Full Text | PDF (592 KB)
Targeting Chemokine Receptors in HIV: A Status Report Shawn E. Kuhmann , Oliver Hartley Annual Review of Pharmacology and Toxicology, Vol. 48: 425-461 (Volume publication date February 2008)
Abstract | Full Text | PDF (501 KB)
Biomarkers of Acute Kidney Injury Vishal S. Vaidya , Michael A. Ferguson , Joseph V. Bonventre Annual Review of Pharmacology and Toxicology, Vol. 48: 463-493 (Volume publication date February 2008)
Abstract | Full Text | PDF (386 KB)
The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy Matthew D. Hall , Mitsunori Okabe , Ding-Wu Shen , Xing-Jie Liang , Michael M. Gottesman Annual Review of Pharmacology and Toxicology, Vol. 48: 495-535 (Volume publication date February 2008)
Abstract | Full Text | PDF (435 KB) | Supplemental Material
Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications Aylin C. Hanyaloglu , Mark von Zastrow Annual Review of Pharmacology and Toxicology, Vol. 48: 537-568 (Volume publication date February 2008)
Abstract | Full Text | PDF (513 KB)
PKC Isozymes in Chronic Cardiac Disease: Possible Therapeutic Targets? Eric Churchill , Grant Budas , Alice Vallentin , Tomoyoshi Koyanagi , Daria Mochly-Rosen Annual Review of Pharmacology and Toxicology, Vol. 48: 569-599 (Volume publication date February 2008)
Abstract | Full Text | PDF (571 KB)
G ProteinCoupled Receptor Sorting to Endosomes and Lysosomes Adriano Marchese, May M. Paing, Brenda R.S. Temple, JoAnn Trejo Annual Review of Pharmacology and Toxicology, Vol. 48: 601-629 (Volume publication date February 2008)
Abstract | Full Text | PDF (1114 KB) | Supplemental Material
Strategic Approach to Fit-for-Purpose Biomarkers in Drug Development John A. Wagner Annual Review of Pharmacology and Toxicology, Vol. 48: 631-651 (Volume publication date February 2008)
Abstract | Full Text | PDF (347 KB)
Metabolomics: A Global Biochemical Approach to Drug Response and Disease Rima Kaddurah-Daouk, Bruce S. Kristal, Richard M. Weinshilboum Annual Review of Pharmacology and Toxicology, Vol. 48: 653-683 (Volume publication date February 2008)

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